[Creative PEGWorks 한국공식대리점] Hyaluronic Acid-Amine

어스바이오는 Creative PEGWorks 한국 공식 대리점으로서 모든 제품을 전문적으로 취급 및 공급하고 있습니다.
Creative PEGWorks의 Amine Hyaluronic Acid 제품을 소개드립니다.
 

 

Product Information:

Hyaluronic Acid은 아민(amine) 기로 기능화되거나 유도체화(derivatized)됩니다. 아민 기는 아마이드 결합을 통해 HA에 접합됩니다. 아민 NH2 치환 비율이 더 낮거나 높은 HA-Amine 유도체(예: 1% 및 10%)는 맞춤 합성 서비스를 통해 제공될 수 있습니다.

• 순도: >95%
• 치환도(DoS): 5 mol %

Properties

• Name and Source: Hyaluronic acid (HA, Hyaluronan, Hyaluronate) is an anionic, non-sulfated glycosaminoglycan distributed widely throughout connective, epithelial, and neural tissues. CAS# 9004-61-9. Our HA products are produced via microbial fermentation. See Documents section for details.
• Appearance: White, lyophilized powder, except dye-labeled HA reagents.
• Solubility: Soluble in water and the solubility data varies with MW. Higher MW results in lowered solubility. Typically solubility ranges 5-50 mg/mL, that is, 0.5%-5%. Buffered solution at pH >6 enhances solubility due to deprotonation of carboxylic acid groups and formation of carboxylate salts. HA derivatives with hydrophobic groups will lower the solubility in water, and adding alcohol or DMSO to an alcohol-water or DMSO-water mixture can dramatically improve the solubility up to 200 mg/mL (20%).
• Degree of Substitution (DoS): The standard DoS is 5% by default. Product variants with special DoS other than 5% is indicated in the product name and catalog number. For example, HA-301-30% means that the DoS is 30% for this particular product.

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